STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08574.1TIGRFAM: KH-domain/beta-lactamase-domain protein, archaea; PFAM: Beta-lactamase-like; K Homology, type 1, subgroup; RNA-metabolising metallo-beta-lactamase; KEGG: mmg:MTBMA_c15810 metal-dependent RNase; SMART: Beta-lactamase-like; K Homology. (634 aa)    
Predicted Functional Partners:
psmB
Proteasome endopeptidase complex, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
   
 0.820
ADZ10401.1
Shwachman-Bodian-Diamond syndrome protein; KEGG: mth:MTH685 putative RNA-associated protein; TIGRFAM: Ribosome maturation protein SBDS; PFAM: Ribosome maturation protein SBDS, N-terminal; Ribosome maturation protein SBDS, C-terminal.
 
   
 0.644
ADZ10396.1
Brix domain protein; Probably involved in the biogenesis of the ribosome.
   
  
 0.640
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
     
 0.615
rrp42
3' exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
 
   
 0.612
ADZ10405.1
Protein of unknown function DUF54; PFAM: Uncharacterised protein family UPF0201; KEGG: mfv:Mfer_0818 hypothetical protein.
  
   
 0.609
rnj
Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
      
0.584
rrp41
Exosome complex exonuclease 1; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
     
 0.562
csl4
RNA-binding domain, S1; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
      
 0.550
purM
TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: msi:Msm_1039 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase-related protein; AIR synthase-related protein, C-terminal.
       0.536
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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