| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ08361.1 | ADZ08590.1 | Metbo_0108 | Metbo_0338 | tRNA (adenine-N(1)-)-methyltransferase; Manually curated; KEGG: mth:MTH1414 protein-L-isoaspartate methyltransferase-like protein; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase. | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | 0.646 |
| ADZ08361.1 | ADZ08744.1 | Metbo_0108 | Metbo_0492 | tRNA (adenine-N(1)-)-methyltransferase; Manually curated; KEGG: mth:MTH1414 protein-L-isoaspartate methyltransferase-like protein; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase. | Protein of unknown function UPF0021; KEGG: mru:mru_0562 PP-loop family protein; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | 0.611 |
| ADZ08361.1 | rlmE | Metbo_0108 | Metbo_0531 | tRNA (adenine-N(1)-)-methyltransferase; Manually curated; KEGG: mth:MTH1414 protein-L-isoaspartate methyltransferase-like protein; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase. | Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.794 |
| ADZ08361.1 | truD | Metbo_0108 | Metbo_0011 | tRNA (adenine-N(1)-)-methyltransferase; Manually curated; KEGG: mth:MTH1414 protein-L-isoaspartate methyltransferase-like protein; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase. | tRNA pseudouridine synthase D; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.474 |
| ADZ08589.1 | ADZ08590.1 | Metbo_0337 | Metbo_0338 | Protein of unknown function DUF77; KEGG: mmg:MTBMA_c15640 hypothetical protein; TIGRFAM: Protein of unknown function DUF77; PFAM: Protein of unknown function DUF77. | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | 0.669 |
| ADZ08590.1 | ADZ08361.1 | Metbo_0338 | Metbo_0108 | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | tRNA (adenine-N(1)-)-methyltransferase; Manually curated; KEGG: mth:MTH1414 protein-L-isoaspartate methyltransferase-like protein; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase. | 0.646 |
| ADZ08590.1 | ADZ08589.1 | Metbo_0338 | Metbo_0337 | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | Protein of unknown function DUF77; KEGG: mmg:MTBMA_c15640 hypothetical protein; TIGRFAM: Protein of unknown function DUF77; PFAM: Protein of unknown function DUF77. | 0.669 |
| ADZ08590.1 | ADZ08744.1 | Metbo_0338 | Metbo_0492 | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | Protein of unknown function UPF0021; KEGG: mru:mru_0562 PP-loop family protein; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | 0.574 |
| ADZ08590.1 | ADZ09451.1 | Metbo_0338 | Metbo_1208 | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: mbn:Mboo_1985 UBA/ThiF-type NAD/FAD binding protein. | 0.612 |
| ADZ08590.1 | ADZ10146.1 | Metbo_0338 | Metbo_1926 | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | Histone acetyltransferase, ELP3 family; SMART: Elongator protein 3/MiaB/NifB; TIGRFAM: Histone acetyltransferase ELP3; KEGG: mst:Msp_0372 histone acetyltransferase; PFAM: Radical SAM; GCN5-related N-acetyltransferase (GNAT) domain. | 0.625 |
| ADZ08590.1 | ADZ10696.1 | Metbo_0338 | Metbo_2483 | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | PFAM: UBA/THIF-type NAD/FAD binding fold; KEGG: mmg:MTBMA_c01580 molybdopterin biosynthesis protein MoeB. | 0.632 |
| ADZ08590.1 | flpA | Metbo_0338 | Metbo_0305 | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.546 |
| ADZ08590.1 | rlmE | Metbo_0338 | Metbo_0531 | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.495 |
| ADZ08590.1 | serS | Metbo_0338 | Metbo_2230 | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.526 |
| ADZ08590.1 | truD | Metbo_0338 | Metbo_0011 | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | tRNA pseudouridine synthase D; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.554 |
| ADZ08744.1 | ADZ08361.1 | Metbo_0492 | Metbo_0108 | Protein of unknown function UPF0021; KEGG: mru:mru_0562 PP-loop family protein; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | tRNA (adenine-N(1)-)-methyltransferase; Manually curated; KEGG: mth:MTH1414 protein-L-isoaspartate methyltransferase-like protein; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase. | 0.611 |
| ADZ08744.1 | ADZ08590.1 | Metbo_0492 | Metbo_0338 | Protein of unknown function UPF0021; KEGG: mru:mru_0562 PP-loop family protein; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | 0.574 |
| ADZ08744.1 | ADZ09451.1 | Metbo_0492 | Metbo_1208 | Protein of unknown function UPF0021; KEGG: mru:mru_0562 PP-loop family protein; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: mbn:Mboo_1985 UBA/ThiF-type NAD/FAD binding protein. | 0.590 |
| ADZ08744.1 | ADZ10146.1 | Metbo_0492 | Metbo_1926 | Protein of unknown function UPF0021; KEGG: mru:mru_0562 PP-loop family protein; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | Histone acetyltransferase, ELP3 family; SMART: Elongator protein 3/MiaB/NifB; TIGRFAM: Histone acetyltransferase ELP3; KEGG: mst:Msp_0372 histone acetyltransferase; PFAM: Radical SAM; GCN5-related N-acetyltransferase (GNAT) domain. | 0.763 |
| ADZ08744.1 | ADZ10696.1 | Metbo_0492 | Metbo_2483 | Protein of unknown function UPF0021; KEGG: mru:mru_0562 PP-loop family protein; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase. | PFAM: UBA/THIF-type NAD/FAD binding fold; KEGG: mmg:MTBMA_c01580 molybdopterin biosynthesis protein MoeB. | 0.654 |
