STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08616.1PFAM: Acylneuraminate cytidylyltransferase; KEGG: mst:Msp_0310 GTP:adenosylcobinamide-phosphate guanylyltransferase. (220 aa)    
Predicted Functional Partners:
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.956
ADZ08617.1
PRC-barrel domain protein; PFAM: PRC-barrel; KEGG: mmg:MTBMA_c15350 hypothetical protein.
  
    0.930
cobD
Cobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
  0.925
ADZ08615.1
Methanogenesis marker protein 14; KEGG: mth:MTH1153 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP016937, methanogenesis; PFAM: Uncharacterised conserved protein UCP016937, methanogenesis.
       0.878
ADZ08353.1
UPF0284 protein; TIGRFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative; HAMAP: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative; KEGG: mmg:MTBMA_c00140 hypothetical protein; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like; Belongs to the UPF0284 family.
 
     0.573
ADZ10405.1
Protein of unknown function DUF54; PFAM: Uncharacterised protein family UPF0201; KEGG: mfv:Mfer_0818 hypothetical protein.
 
   
 0.481
ADZ08603.1
KEGG: mmg:MTBMA_c15500 methyl-coenzyme M reductase I, subunit epsilon; TIGRFAM: Methyl-coenzyme M reductase, protein C; PFAM: Methyl-coenzyme M reductase, protein C.
 
     0.465
ADZ08614.1
Anion transporter; KEGG: mth:MTH788 sodium/dicarboxylate or sulfate cotransporter; TIGRFAM: Sodium/sulphate symporter; PFAM: Sodium/sulphate symporter.
       0.462
ADZ08605.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
     0.461
ADZ08639.1
PFAM: Phosphatidylglycerophosphatase A; KEGG: mfv:Mfer_0120 alpha-ribazole phosphatase cobz.
 
     0.459
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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