STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
queCexsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (228 aa)    
Predicted Functional Partners:
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.996
ADZ08544.1
KEGG: mmg:MTBMA_c16130 6-pyruvoyl tetrahydrobiopterin synthase.
 
  
 0.994
ADZ08643.1
UPF0272 protein; TIGRFAM: Uncharacterised protein family UPF0272; HAMAP: Uncharacterised protein family UPF0272; KEGG: mth:MTH1109 hypothetical protein; PFAM: Uncharacterised protein family UPF0272; Belongs to the LarC family.
       0.915
tgtA
7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
 
   
 0.721
ADZ08645.1
PFAM: 4-vinyl reductase, 4VR; KEGG: mmg:MTBMA_c12390 hypothetical protein.
       0.693
ADZ08485.1
PFAM: 4Fe-4S binding domain; KEGG: amt:Amet_1416 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
     
 0.575
ADZ08642.1
KEGG: mbn:Mboo_0945 cytosine deaminase; PFAM: CMP/dCMP deaminase, zinc-binding.
       0.559
ADZ10744.1
TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; KEGG: mmg:MTBMA_c01230 anaerobic ribonucleotide-triphosphate reductase; PFAM: ATP-cone.
       0.453
cofC
2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
      
 0.452
ADZ08439.1
PFAM: Natural resistance-associated macrophage protein; KEGG: mst:Msp_1554 Mn2+/Fe2+ transporter.
 
   
 0.417
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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