| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ08298.1 | ADZ08637.1 | Metbo_0045 | Metbo_0385 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.640 |
| ADZ08298.1 | ADZ08851.1 | Metbo_0045 | Metbo_0600 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.686 |
| ADZ08298.1 | ADZ08932.1 | Metbo_0045 | Metbo_0681 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | SMART: Nucleotide binding protein, PINc; KEGG: mru:mru_1781 hypothetical protein. | 0.592 |
| ADZ08298.1 | ADZ09239.1 | Metbo_0045 | Metbo_0992 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | PFAM: Cytidylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; KEGG: mmg:MTBMA_c06000 nicotinamide-nucleotide adenylyltransferase. | 0.613 |
| ADZ08298.1 | ADZ10341.1 | Metbo_0045 | Metbo_2122 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | GHMP kinase; KEGG: mst:Msp_1187 kinase; manually curated; PFAM: GHMP kinase. | 0.597 |
| ADZ08298.1 | pfdB | Metbo_0045 | Metbo_2179 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | Prefoldin subunit beta; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.520 |
| ADZ08298.1 | tiaS | Metbo_0045 | Metbo_0426 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.692 |
| ADZ08637.1 | ADZ08298.1 | Metbo_0385 | Metbo_0045 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | 0.640 |
| ADZ08637.1 | ADZ08851.1 | Metbo_0385 | Metbo_0600 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.549 |
| ADZ08637.1 | ADZ08932.1 | Metbo_0385 | Metbo_0681 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | SMART: Nucleotide binding protein, PINc; KEGG: mru:mru_1781 hypothetical protein. | 0.588 |
| ADZ08637.1 | ADZ09239.1 | Metbo_0385 | Metbo_0992 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | PFAM: Cytidylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; KEGG: mmg:MTBMA_c06000 nicotinamide-nucleotide adenylyltransferase. | 0.660 |
| ADZ08637.1 | ADZ10341.1 | Metbo_0385 | Metbo_2122 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | GHMP kinase; KEGG: mst:Msp_1187 kinase; manually curated; PFAM: GHMP kinase. | 0.405 |
| ADZ08637.1 | pfdB | Metbo_0385 | Metbo_2179 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Prefoldin subunit beta; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.689 |
| ADZ08637.1 | tiaS | Metbo_0385 | Metbo_0426 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.674 |
| ADZ08677.1 | ADZ08679.1 | Metbo_0425 | Metbo_0427 | HAMAP: HTH transcriptional regulator, cro/C1-type DNA-binding domain-containing; PFAM: Helix-turn-helix type 3; KEGG: mmg:MTBMA_c13530 transcriptional regulator; SMART: Helix-turn-helix type 3. | MmgE/PrpD family protein; PFAM: MmgE/PrpD; KEGG: mfv:Mfer_0669 MmgE/PrpD family protein. | 0.481 |
| ADZ08677.1 | tiaS | Metbo_0425 | Metbo_0426 | HAMAP: HTH transcriptional regulator, cro/C1-type DNA-binding domain-containing; PFAM: Helix-turn-helix type 3; KEGG: mmg:MTBMA_c13530 transcriptional regulator; SMART: Helix-turn-helix type 3. | Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.796 |
| ADZ08679.1 | ADZ08677.1 | Metbo_0427 | Metbo_0425 | MmgE/PrpD family protein; PFAM: MmgE/PrpD; KEGG: mfv:Mfer_0669 MmgE/PrpD family protein. | HAMAP: HTH transcriptional regulator, cro/C1-type DNA-binding domain-containing; PFAM: Helix-turn-helix type 3; KEGG: mmg:MTBMA_c13530 transcriptional regulator; SMART: Helix-turn-helix type 3. | 0.481 |
| ADZ08679.1 | tiaS | Metbo_0427 | Metbo_0426 | MmgE/PrpD family protein; PFAM: MmgE/PrpD; KEGG: mfv:Mfer_0669 MmgE/PrpD family protein. | Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.742 |
| ADZ08851.1 | ADZ08298.1 | Metbo_0600 | Metbo_0045 | UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | 0.686 |
| ADZ08851.1 | ADZ08637.1 | Metbo_0600 | Metbo_0385 | UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.549 |