STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
atpAV-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (583 aa)    
Predicted Functional Partners:
ADZ08684.1
V-type ATPase 116 kDa subunit; KEGG: mth:MTH960 V-type ATP synthase subunit I; manually curated; PFAM: ATPase, V0/A0 complex, 116kDa subunit; Belongs to the V-ATPase 116 kDa subunit family.
 
 0.999
ADZ08685.1
KEGG: mmg:MTBMA_c13450 A1AO ATPase, subunit K; HAMAP: ATPase, F0 complex, subunit C; PFAM: ATPase, F0/V0 complex, subunit C; Belongs to the V-ATPase proteolipid subunit family.
 
 0.999
atpE
V-type proton ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
atpC
V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
atpF
V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 0.999
atpB
V-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
 
0.999
atpD
V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
ADZ08683.1
TIGRFAM: ATPase, A1A0, subunit H; KEGG: mth:MTH961 hypothetical protein.
   
 0.997
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
   
 
 0.944
ADZ08692.1
PFAM: Domain of unknown function DUF22; KEGG: mth:MTH952 hypothetical protein.
  
    0.934
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.