STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08728.1PFAM: Citrate synthase-like; KEGG: mmg:MTBMA_c03010 citrate synthase-related protein; Belongs to the citrate synthase family. (259 aa)    
Predicted Functional Partners:
sucC
Succinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 
 0.960
ADZ08830.1
HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily.
  
 
 0.930
ADZ10085.1
Methylisocitrate lyase; KEGG: ccb:Clocel_0283 2,3-dimethylmalate lyase.
 
 
 0.860
ADZ08423.1
KEGG: mru:mru_0103 3-isopropylmalate dehydrogenase LeuB; PFAM: Isocitrate/isopropylmalate dehydrogenase.
 
 0.833
ADZ08832.1
TIGRFAM: Isopropylmalate/isohomocitrate dehydrogenase; KEGG: mth:MTH184 multifunctional 3-isopropylmalate dehydrogenase/D-malate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase.
 
 0.833
ADZ10331.1
TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; KEGG: mmh:Mmah_0726 succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: Ferredoxin.
  
 
 0.828
ADZ08679.1
MmgE/PrpD family protein; PFAM: MmgE/PrpD; KEGG: mfv:Mfer_0669 MmgE/PrpD family protein.
 
  
 0.821
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 
 0.780
ADZ08374.1
PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; KEGG: rci:RCIX757 peptidyl-prolyl cis-trans isomerase B (cyclophilin type).
  
 
 0.747
ADZ08845.1
YbhB YbcL family protein; KEGG: sat:SYN_03131 phosphatidylethanolamine-binding protein; TIGRFAM: YbhB/YbcL; PFAM: Phosphatidylethanolamine-binding protein PEBP.
  
 
 0.745
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.