STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08745.1PFAM: ThiamineS; KEGG: mru:mru_0563 thiamine biosynthesis protein ThiS. (66 aa)    
Predicted Functional Partners:
ADZ08744.1
Protein of unknown function UPF0021; KEGG: mru:mru_0562 PP-loop family protein; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase.
  
 
 0.964
ADZ09509.1
Hypothetical protein.
     
  0.900
ADZ09451.1
PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: mbn:Mboo_1985 UBA/ThiF-type NAD/FAD binding protein.
  
 
 0.893
ADZ10696.1
PFAM: UBA/THIF-type NAD/FAD binding fold; KEGG: mmg:MTBMA_c01580 molybdopterin biosynthesis protein MoeB.
  
 
 0.893
ADZ09355.1
KEGG: cte:CT1466 TIR domain-containing protein; PFAM: Toll-Interleukin receptor; SMART: Toll-Interleukin receptor.
  
 
 0.816
ADZ08673.1
Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; KEGG: mmg:MTBMA_c13570 hypothetical protein.
  
 
 0.801
ADZ08590.1
Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase.
  
 
 0.771
ADZ09258.1
TIGRFAM: Phosphomethylpyrimidine kinase type-2; KEGG: mfv:Mfer_1038 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
  
    0.731
ADZ08747.1
PFAM: Domain of unknown function DUF89; KEGG: mth:MTH1744 hypothetical protein.
     
 0.702
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.667
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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