Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08747.1PFAM: Domain of unknown function DUF89; KEGG: mth:MTH1744 hypothetical protein. (290 aa)    
Predicted Functional Partners:
ADZ08745.1
PFAM: ThiamineS; KEGG: mru:mru_0563 thiamine biosynthesis protein ThiS.
     
 0.733
ADZ08748.1
PFAM: Thioredoxin domain; KEGG: mth:MTH1745 protein disulphide isomerase.
 
   
 0.616
ADZ08746.1
PFAM: Peptidase M50; KEGG: pab:PAB1063 hypothetical protein.
       0.598
ADZ08750.1
PFAM: Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal; NADP oxidoreductase, coenzyme F420-dependent; KEGG: mmg:MTBMA_c03230 dehydrogenase.
       0.592
ADZ08744.1
Protein of unknown function UPF0021; KEGG: mru:mru_0562 PP-loop family protein; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase.
       0.582
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
     
 0.566
ADZ08749.1
PFAM: Cytochrome c assembly protein, transmembrane domain; KEGG: mmg:MTBMA_c03220 cytochrome c-type biogenesis protein.
       0.524
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
     0.419
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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