Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08758.1PFAM: Radical SAM; KEGG: kcr:Kcr_0677 radical SAM domain-containing protein. (295 aa)    
Predicted Functional Partners:
ADZ09783.1
KEGG: mbu:Mbur_2163 hypothetical protein.
       0.659
ADZ10368.1
Type II site-specific deoxyribonuclease; KEGG: abi:Aboo_1333 protein of unknown function DUF450; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; DNA methylase, adenine-specific.
       0.659
ADZ10573.1
Protein of unknown function DUF650; Involved in DNA damage repair.
       0.541
ADZ08973.1
PFAM: Methyltransferase type 11; KEGG: npu:Npun_F4534 methyltransferase type 11.
       0.535
ADZ08757.1
PFAM: Domain of unknown function DUF815; KEGG: mst:Msp_1313 ATPase.
 
     0.418
ADZ08708.1
KEGG: rci:LRC130 hypothetical protein.
 
   
 0.415
ADZ08987.1
HAMAP: Uncharacterised protein family UPF0173, metal-dependent hydrolase; PFAM: Beta-lactamase-like; KEGG: mru:mru_0834 metallo-beta-lactamase superfamily protein; SMART: Beta-lactamase-like; Belongs to the UPF0173 family.
 
     0.401
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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