Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08760.1TIGRFAM: Methyl coenzyme M reductase system, component A2; PFAM: ABC transporter-like; KEGG: mmg:MTBMA_c13970 methyl-coenzyme M reductase, component A2; SMART: ATPase, AAA+ type, core. (530 aa)    
Predicted Functional Partners:
ADZ08603.1
KEGG: mmg:MTBMA_c15500 methyl-coenzyme M reductase I, subunit epsilon; TIGRFAM: Methyl-coenzyme M reductase, protein C; PFAM: Methyl-coenzyme M reductase, protein C.
 
 
 
 0.941
ADZ08598.1
Methanogenesis marker protein 7; TIGRFAM: Uncharacterised conserved protein UCP019164, methanogenesis; KEGG: mmg:MTBMA_c15570 methyl coenzyme M reductase II, operon protein C.
 
 
 
 0.936
ADZ08605.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
 
 
 0.933
ADZ08940.1
Methanogenesis marker protein 17; KEGG: mth:MTH1870 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP019464, methanogenesis; PFAM: Uncharacterised conserved protein UCP019464, methanogenesis.
 
 
 
 0.931
ADZ10495.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
 
 
 0.929
ADZ08604.1
TIGRFAM: Methyl-coenzyme M reductase, gamma subunit; KEGG: mth:MTH1165 methyl coenzyme M reductase I, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit.
 
 
   0.918
ADZ10494.1
TIGRFAM: Methyl-coenzyme M reductase, gamma subunit; KEGG: mth:MTH1130 methyl coenzyme M reductase II, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit.
 
 
   0.918
ADZ08601.1
TIGRFAM: Methyl-coenzyme M reductase, beta subunit; KEGG: mmg:MTBMA_c15520 methyl-coenzyme M reductase I, subunit beta; PFAM: Methyl-coenzyme M reductase, beta subunit, C-terminal; Methyl-coenzyme M reductase, beta subunit, N-terminal.
 
 
   0.901
ADZ10492.1
TIGRFAM: Methyl-coenzyme M reductase, beta subunit; KEGG: mfv:Mfer_0731 methyl-coenzyme m reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit, C-terminal; Methyl-coenzyme M reductase, beta subunit, N-terminal.
 
 
   0.901
ADZ08761.1
UPF0251 protein; KEGG: mmg:MTBMA_c15550 DNA-binding protein; HAMAP: Uncharacterised protein family UPF0251; PFAM: Uncharacterised protein family UPF0251; Belongs to the UPF0251 family.
  
    0.869
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.