Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08761.1UPF0251 protein; KEGG: mmg:MTBMA_c15550 DNA-binding protein; HAMAP: Uncharacterised protein family UPF0251; PFAM: Uncharacterised protein family UPF0251; Belongs to the UPF0251 family. (203 aa)    
Predicted Functional Partners:
ADZ08760.1
TIGRFAM: Methyl coenzyme M reductase system, component A2; PFAM: ABC transporter-like; KEGG: mmg:MTBMA_c13970 methyl-coenzyme M reductase, component A2; SMART: ATPase, AAA+ type, core.
  
    0.869
ADZ08641.1
PFAM: Uncharacterised protein family, nitrogen regulatory protein PII-related; KEGG: mmg:MTBMA_c14940 transcriptional regulatory protein.
  
    0.842
ADZ10652.1
SMART: ATPase, AAA+ type, core; TIGRFAM: Methyl coenzyme M reductase system, component A2; KEGG: mmg:MTBMA_c13970 methyl-coenzyme M reductase, component A2; PFAM: ABC transporter-like.
  
    0.655
ADZ09488.1
PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; KEGG: mth:MTH1177 hypothetical protein.
 
  
 0.559
mer
5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
       0.447
ADZ10310.1
KEGG: dae:Dtox_1747 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like.
 
     0.446
ADZ08759.1
TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold; ATPase-like, ATP-binding domain; KEGG: mmg:MTBMA_c12200 sensory transduction histidine kinase; SMART: PAS; ATPase-like, ATP-binding domain.
       0.403
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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