STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mptEProtein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (273 aa)    
Predicted Functional Partners:
mptD
Protein of unknown function DUF372; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
 
  
 0.967
ADZ10310.1
KEGG: dae:Dtox_1747 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like.
    
  0.902
ADZ08813.1
Cell division control protein 6-like protein; Involved in regulation of DNA replication.
       0.733
aroK
PFAM: GHMP kinase; GHMP kinase, C-terminal; TIGRFAM: Shikimate kinase, archaea; HAMAP: Shikimate kinase; KEGG: mfv:Mfer_0680 shikimate kinase.
  
     0.589
ADZ08815.1
Serine--pyruvate transaminase; KEGG: mmg:MTBMA_c01880 aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase.
       0.559
mptA
Protein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
 
   
 0.547
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
     0.538
ADZ08851.1
UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
     0.531
ADZ08950.1
PFAM: Queuine/other tRNA-ribosyltransferase; KEGG: mru:mru_0814 archaeosine tRNA-ribosyltransferase TgtA1.
  
     0.504
tiaS
Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
     0.501
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.