STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
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Experiments
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[Homology]
Score
pdxTGlutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (191 aa)    
Predicted Functional Partners:
pdxS
Pyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
 
 0.998
ADZ08827.1
PFAM: Glutamine amidotransferase, class-II; KEGG: mmg:MTBMA_c06420 glutamate synthase, subunit 1.
       0.916
ADZ09513.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: mmg:MTBMA_c08030 energy-converting hydrogenase T, subunit T; Belongs to the carbohydrate kinase PfkB family.
    
 0.820
ADZ08825.1
Coenzyme F420 hydrogenase; KEGG: mmg:MTBMA_c06440 F420-dependent glutamate synthase; PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; 4Fe-4S binding domain; Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal.
       0.812
ADZ08826.1
PFAM: Glutamate synthase, alpha subunit, C-terminal; KEGG: mth:MTH192 tungsten formylmethanofuran dehydrogenase, subunit C-like protein.
       0.812
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
 0.806
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
    
  0.804
ADZ10674.1
KEGG: mmg:MTBMA_c01700 phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; Belongs to the phosphohexose mutase family.
     
  0.800
ADZ08824.1
KEGG: mmg:MTBMA_c06450 glutamate synthase, subunit 2; PFAM: Glutamate synthase, central-C; 4Fe-4S binding domain; Belongs to the glutamate synthase family.
     
 0.799
ADZ10697.1
TIGRFAM: Glutamine synthetase type I; KEGG: mth:MTH1570 glutamine synthetase; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp.
     
 0.659
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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