STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08834.1PFAM: Protein of unknown function DUF434; KEGG: mfv:Mfer_0750 hypothetical protein. (221 aa)    
Predicted Functional Partners:
ADZ08835.1
Protein of unknown function DUF47; KEGG: mmg:MTBMA_c02670 hypothetical protein; TIGRFAM: Protein of unknown function DUF47; PFAM: Putitive phosphate transport regulator.
       0.852
ADZ08836.1
PFAM: Domain of unknown function DUF357; KEGG: mth:MTH1690 hypothetical protein.
       0.637
ADZ08301.1
PFAM: Major facilitator superfamily MFS-1; KEGG: mru:mru_1002 MFS transporter.
  
    0.457
ADZ10396.1
Brix domain protein; Probably involved in the biogenesis of the ribosome.
  
     0.457
ADZ08837.1
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: mru:mru_0503 phosphatidylglycerophosphate synthase PgsA; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.456
ADZ08453.1
UPF0215 protein; Manually curated; HAMAP: Protein of unknown function DUF99; KEGG: mmg:MTBMA_c17020 hypothetical protein; PFAM: Protein of unknown function DUF99; Belongs to the UPF0215 family.
 
     0.454
ADZ10082.1
PFAM: Protein of unknown function DUF166; KEGG: mth:MTH1356 hypothetical protein.
 
     0.441
rtcA
RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
     0.412
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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