Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08836.1PFAM: Domain of unknown function DUF357; KEGG: mth:MTH1690 hypothetical protein. (77 aa)    
Predicted Functional Partners:
ADZ08837.1
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: mru:mru_0503 phosphatidylglycerophosphate synthase PgsA; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.816
ADZ08835.1
Protein of unknown function DUF47; KEGG: mmg:MTBMA_c02670 hypothetical protein; TIGRFAM: Protein of unknown function DUF47; PFAM: Putitive phosphate transport regulator.
       0.715
ADZ08834.1
PFAM: Protein of unknown function DUF434; KEGG: mfv:Mfer_0750 hypothetical protein.
       0.641
ADZ08838.1
Sua5/YciO/YrdC/YwlC family protein; KEGG: mfv:Mfer_1131 translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC; PFAM: Sua5/YciO/YrdC, N-terminal.
       0.499
dphB
Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
       0.402
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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