Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
argHPFAM: Lyase 1, N-terminal; TIGRFAM: Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; KEGG: mmg:MTBMA_c07190 argininosuccinate lyase. (469 aa)    
Predicted Functional Partners:
argG
PFAM: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; KEGG: mth:MTH1254 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.999
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
  
 0.976
argD
PFAM: Aminotransferase class-III; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; KEGG: mfv:Mfer_0532 acetylornithine aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.969
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.968
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
  
 0.947
ADZ08853.1
SMART: RNA-binding domain, S1; TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA-binding domain.
 
 
   0.932
ADZ08254.1
KEGG: mth:MTH1537 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Lyase 1, N-terminal; Adenylosuccinate lyase C-terminal metazoa/fungi; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
  
0.929
ADZ08343.1
PFAM: Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; TIGRFAM: Ornithine carbamoyltransferase; HAMAP: Ornithine carbamoyltransferase; KEGG: mfv:Mfer_0050 ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
  
 0.924
ADZ10330.1
KEGG: gtn:GTNG_2275 aspartate ammonia-lyase; PFAM: Lyase 1, N-terminal; Fumarase C, C-terminal.
    
0.916
ADZ08454.1
PFAM: NUDIX hydrolase domain; KEGG: mst:Msp_1534 putative ADP-ribose pyrophosphatase.
    
 0.884
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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