STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08870.1PFAM: Xylose isomerase, TIM barrel domain; KEGG: mfv:Mfer_1192 xylose isomerase domain protein tim barrel. (251 aa)    
Predicted Functional Partners:
ADZ08871.1
KEGG: mth:MTH246 ATPase; PFAM: PilT protein, N-terminal; SMART: Nucleotide binding protein, PINc.
       0.905
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
       0.905
ADZ10554.1
Oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; KEGG: mth:MTH875 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein.
  
  
 0.883
hisS
ATP phosphoribosyltransferase regulatory subunit; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; HAMAP: ATP phosphoribosyltransferase regulatory subunit; Histidyl-tRNA synthetase, class IIa, subgroup; KEGG: mth:MTH244 histidyl-tRNA synthetase.
       0.832
ADZ09513.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: mmg:MTBMA_c08030 energy-converting hydrogenase T, subunit T; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.685
endA
tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
 
     0.677
ADZ08909.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: mfv:Mfer_0308 PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.672
ADZ08869.1
NADPH-dependent F420 reductase; KEGG: mth:MTH248 hypothetical protein; TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent.
  
    0.660
ADZ10662.1
TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1; KEGG: mmg:MTBMA_c06610 DNA lyase; PFAM: Endonuclease/exonuclease/phosphatase.
     
 0.620
ADZ10391.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: mst:Msp_1258 ribokinase.
  
  
 0.598
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: medium (74%) [HD]