STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08877.1KEGG: mth:MTH561 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00267; PFAM: Domain of unknown function DUF125, transmembrane. (192 aa)    
Predicted Functional Partners:
ADZ10545.1
PFAM: Protein of unknown function DUF211; KEGG: mmg:MTBMA_c12840 hypothetical protein.
 
     0.749
ADZ08878.1
TIGRFAM: Hydroxymethylglutaryl-CoA reductase, eukaryotic/arcaheal type; KEGG: mfv:Mfer_0012 3-hydroxy-3-methylglutaryl-coenzyme a reductase; PFAM: Hydroxymethylglutaryl-CoA reductase, class I/II; Belongs to the HMG-CoA reductase family.
       0.735
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.617
ADZ08986.1
KEGG: mmg:MTBMA_c04730 hypothetical protein.
  
     0.542
ADZ10027.1
APHP domain protein; PFAM: APHP; KEGG: mmg:MTBMA_c13780 hypothetical protein.
  
     0.527
ADZ08989.1
PFAM: Uncharacterised conserved protein UCP004977; KEGG: mmg:MTBMA_c04760 hypothetical protein.
  
     0.481
ADZ10048.1
PFAM: Peptidase C60, sortase A/B; KEGG: mmg:MTBMA_c03990 sortase related protein.
  
     0.467
ADZ08827.1
PFAM: Glutamine amidotransferase, class-II; KEGG: mmg:MTBMA_c06420 glutamate synthase, subunit 1.
 
     0.460
ADZ08394.1
PFAM: Protein of unknown function DUF166; KEGG: mth:MTH1356 hypothetical protein.
  
     0.453
ADZ09010.1
Protein of unknown function DUF88; KEGG: mmg:MTBMA_c04840 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00288; PFAM: Domain of unknown function DUF88.
 
     0.450
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.