Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
htpXProtease htpX; KEGG: mmg:MTBMA_c09550 heat shock protein; HAMAP: Peptidase M48, protease HtpX, putative; PFAM: Peptidase M48; Belongs to the peptidase M48B family. (319 aa)    
Predicted Functional Partners:
ADZ08533.1
PFAM: Amino acid-binding ACT; KEGG: mmg:MTBMA_c16230 energy-converting hydrogenase B, subunit Q.
  
    0.800
ADZ10341.1
GHMP kinase; KEGG: mst:Msp_1187 kinase; manually curated; PFAM: GHMP kinase.
  
    0.779
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.690
ilvD
PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: mmg:MTBMA_c00370 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.651
ADZ08417.1
PFAM: Auxin efflux carrier; KEGG: mth:MTH1382 hypothetical protein.
  
  
 0.631
ADZ08830.1
HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily.
  
 0.574
ADZ10105.1
KEGG: mfv:Mfer_0531 atpase associated with various cellular activities aaa_5; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core.
 
  
 0.548
ADZ10270.1
KEGG: mst:Msp_1077 dihydrolipoamide dehydrogenase-related protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.530
ADZ08884.1
PFAM: SNARE associated Golgi protein; KEGG: mfv:Mfer_1129 SNARE associated golgi protein-like protein.
     
 0.484
sucC
Succinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.483
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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