STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08909.1PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: mfv:Mfer_0308 PfkB domain protein; Belongs to the carbohydrate kinase PfkB family. (290 aa)    
Predicted Functional Partners:
hpt
Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
  
 
 0.765
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.756
ADZ08870.1
PFAM: Xylose isomerase, TIM barrel domain; KEGG: mfv:Mfer_1192 xylose isomerase domain protein tim barrel.
 
  
 0.672
ADZ08311.1
PFAM: Xylose isomerase, TIM barrel domain; KEGG: mmg:MTBMA_c00720 sugar phosphate isomerase/epimerase.
 
  
 0.649
hisA
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA; HAMAP: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; KEGG: mmg:MTBMA_c12400 phosphoribosylformimino-5-aminoimidazole ribonucleotide isomerase.
  
  
 0.623
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
    
 0.622
ADZ08908.1
KEGG: mth:MTH1840 cell division inhibitor; TIGRFAM: ATPase, cell division-type, MinD; PFAM: Cobyrinic acid a,c-diamide synthase.
       0.588
ADZ10554.1
Oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; KEGG: mth:MTH875 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein.
  
  
 0.588
ADZ08907.1
Cell division ATPase MinD; KEGG: mmg:MTBMA_c04100 iron-sulfur cluster carrier protein; TIGRFAM: ATPase, cell division-type, MinD; PFAM: Cobyrinic acid a,c-diamide synthase.
       0.528
ADZ08906.1
KEGG: mmg:MTBMA_c04090 hypothetical protein.
       0.524
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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