STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08915.1TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; KEGG: mmg:MTBMA_c04210 thiol:fumarate reductase, subunit B; PFAM: Cysteine-rich domain; Ferredoxin. (498 aa)    
Predicted Functional Partners:
ADZ08296.1
L-aspartate oxidase; KEGG: mfv:Mfer_0085 thiol-driven fumarate reductase, flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal.
 
 
 0.992
ADZ10332.1
TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG: mmh:Mmah_0725 succinate dehydrogenase subunit A; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal.
 
 
 0.990
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
  
 0.971
ADZ10331.1
TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; KEGG: mmh:Mmah_0726 succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: Ferredoxin.
 
0.963
ADZ08681.1
KEGG: mth:MTH963 fumarate hydratase, class I related protein; TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; PFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain.
    
 0.953
ADZ08736.1
TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; KEGG: mth:MTH1735 fumarate hydratase; PFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain.
    
 0.953
sucC
Succinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 
 0.950
ADZ09225.1
Lactate utilization protein B/C; PFAM: Domain of unknown function DUF162; KEGG: mmg:MTBMA_c05900 conserved iron-sulfur cluster binding protein.
 
 0.927
ADZ08914.1
KEGG: mst:Msp_1047 rRNA methylase; TIGRFAM: RNA methyltransferase TrmH, group 1; PFAM: tRNA/rRNA methyltransferase, SpoU.
  
    0.926
ADZ08634.1
PFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; KEGG: msi:Msm_0929 fumarate hydratase, FumA.
    
 0.922
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.