Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ADZ08942.1Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (314 aa)    
Predicted Functional Partners:
ADZ08807.1
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
 
 
 0.975
ADZ08367.1
KEGG: mru:mru_2213 fuculose 1-phosphate aldolase FucA; PFAM: Class II aldolase/adducin, N-terminal.
 
  
 0.888
pheS
TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain 2, bacterial/archaeal; KEGG: mmg:MTBMA_c11370 phenylalanyl-tRNA synthetase, alpha subunit; PFAM: Phenylalanyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
 
    0.705
ADZ08370.1
precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: mfv:Mfer_1185 precorrin-3 methyltransferase; PFAM: Cysteine-rich small domain; Tetrapyrrole methylase.
       0.654
ADZ08941.1
Radical SAM domain protein; KEGG: mth:MTH1871 nitrogenase iron-molybdenum cofactor biosynthesis protein NifB; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB.
       0.654
ADZ08940.1
Methanogenesis marker protein 17; KEGG: mth:MTH1870 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP019464, methanogenesis; PFAM: Uncharacterised conserved protein UCP019464, methanogenesis.
       0.635
ADZ08938.1
Methanogenesis marker protein 5; KEGG: mth:MTH1868 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP018781, methanogenesis; PFAM: Uncharacterised conserved protein UCP018781, methanogenesis.
       0.630
ADZ08939.1
Methanogenesis marker protein 15; KEGG: mth:MTH1869 activator of (R)-2-hydroxyglutaryl-CoA; TIGRFAM: Putative methanogenesis marker protein 15; CoA enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type.
       0.630
ADZ09266.1
KEGG: mba:Mbar_A0261 hypothetical protein.
   
   0.623
ADZ08936.1
KEGG: mfv:Mfer_1092 methanogenesis marker protein 6; TIGRFAM: Uncharacterised conserved protein UCP005642, methanogenesis; PFAM: Uncharacterised conserved protein UCP005642, methanogenesis.
       0.610
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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