Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pgk2KEGG: mmg:MTBMA_c04540 2-phosphoglycerate kinase. (303 aa)    
Predicted Functional Partners:
ADZ08957.1
KEGG: mfv:Mfer_0246 signal transduction protein with cbs domains; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
 
     0.928
cpgS
Cyclic 2,3-diphosphoglycerate synthetase; Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP.
 
   
 0.802
ADZ08582.1
PFAM: Protein of unknown function DUF2100; KEGG: mth:MTH1195 hypothetical protein.
  
    0.589
ADZ08846.1
PFAM: tRNA-specific 2-thiouridylase; KEGG: mru:mru_1475 hypothetical protein.
  
     0.585
ADZ08955.1
Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: mth:MTH1882 hypothetical protein.
       0.583
ADZ10563.1
Conserved hypothetical protein CHP00300; KEGG: mmg:MTBMA_c12620 lysine-oxoglutarate reductase/saccharopine dehydrogenase; TIGRFAM: Conserved hypothetical protein CHP00300; PFAM: LOR/SDH bifunctional enzyme, conserved domain.
  
    0.571
ADZ08632.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
   
 0.549
ADZ10458.1
TIGRFAM: Phosphosulpholactate synthase; KEGG: mth:MTH1674 hypothetical protein; PFAM: (2R)-phospho-3-sulpholactate synthase, ComA.
      
 0.533
ADZ10425.1
PFAM: Methyltransferase type 12; KEGG: mfv:Mfer_1049 RNA methylase.
  
     0.504
ADZ08571.1
KEGG: msi:Msm_0080 sulfopyruvate decarboxylase, ComD; TIGRFAM: Sulfopyruvate decarboxylase, alpha subunit.
      
 0.503
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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