STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ09011.1TIGRFAM: Pyridoxal phosphate-dependent transferase, archaea; KEGG: msi:Msm_0767 selenocysteine synthase, SelA. (386 aa)    
Predicted Functional Partners:
serS
Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
    
 0.937
ADZ10143.1
PFAM: Protein of unknown function DUF2098; KEGG: mth:MTH814 hypothetical protein.
  
    0.845
ADZ09010.1
Protein of unknown function DUF88; KEGG: mmg:MTBMA_c04840 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00288; PFAM: Domain of unknown function DUF88.
   
   0.808
ADZ10736.1
PFAM: HTH transcriptional regulator, LysR; KEGG: mru:mru_0249 transcriptional regulator LysR family.
 
   
 0.765
rtcA
RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
       0.736
ADZ08727.1
PFAM: PhoU; KEGG: mmg:MTBMA_c03000 phosphate transport system regulator.
  
     0.728
ADZ09429.1
KEGG: fpl:Ferp_2212 MoaD family protein; TIGRFAM: MoaD, archaeal; PFAM: ThiamineS.
   
   0.722
ADZ08846.1
PFAM: tRNA-specific 2-thiouridylase; KEGG: mru:mru_1475 hypothetical protein.
  
     0.714
ADZ10454.1
Protein of unknown function DUF129; PFAM: F420-0 gamma-glutamyl ligase-related; KEGG: mth:MTH1670 hypothetical protein.
  
     0.668
ADZ08786.1
PFAM: Oligosaccharyl transferase, STT3 subunit; KEGG: mmg:MTBMA_c02090 oligosaccharyl transferase STT3 subunit related protein.
  
     0.640
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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