Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADZ09014.1TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; KEGG: mmg:MTBMA_c04870 biotin ligase; PFAM: Biotin/lipoate A/B protein ligase; Biotin protein ligase, C-terminal. (323 aa)    
Predicted Functional Partners:
ADZ09015.1
SMART: Biotin carboxylase, C-terminal; TIGRFAM: Acetyl-CoA carboxylase, biotin carboxylase; KEGG: mmg:MTBMA_c04880 pyruvate carboxylase, subunit A; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal.
 0.993
ADZ10539.1
PFAM: BioY protein; KEGG: mmg:MTBMA_c12990 biotin biosynthesis protein.
 
   
 0.825
ADZ08647.1
TIGRFAM: Oxaloacetate decarboxylase, alpha subunit; KEGG: mmg:MTBMA_c14900 pyruvate carboxylase, subunit B; PFAM: Carboxylase, conserved domain; Pyruvate carboxyltransferase; Biotin/lipoyl attachment.
 
     0.692
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.692
ADZ09013.1
LmbE family protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; KEGG: mfv:Mfer_0717 LmbE family protein.
  
  
 0.675
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
     
 0.668
purD
Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: mfv:Mfer_0051 phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
  
 0.608
ADZ08565.1
KEGG: mfv:Mfer_1224 radical sam domain protein; PFAM: Radical SAM; Biotin/thiamin synthesis-associated protein; SMART: Elongator protein 3/MiaB/NifB.
  
  
 0.601
ADZ08593.1
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cbi:CLJ_B1067 CDP-alcohol phosphatidyltransferase family protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.572
ribL
Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
     
 0.547
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.