Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ADZ09016.1PFAM: Methyltransferase type 11; KEGG: msi:Msm_0764 ribosomal L11 RNA methyltransferase (SAM-dependent). (206 aa)    
Predicted Functional Partners:
ADZ08450.1
Universal diphthamide biosynthesis domain-containing protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
 
     0.667
ADZ10321.1
Universal PUA-domain-containing protein; TIGRFAM: Conserved hypothetical protein CHP03684; Uncharacterised domain 2; PFAM: Pseudouridine synthase/archaeosine transglycosylase; KEGG: mth:MTH650 putative RNA-binding protein; SMART: Pseudouridine synthase/archaeosine transglycosylase.
  
   
 0.648
hpt
Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
 
     0.621
pus10
Conserved hypothetical protein CHP01213; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
 
   
 0.615
ADZ08452.1
PFAM: DNA-directed RNA polymerase, dimerisation; KEGG: mth:MTH1317 DNA-dependent RNA polymerase, subunit L.
  
    0.594
ADZ08455.1
Transcription termination factor Tfs; TIGRFAM: DNA-directed RNA polymerase, subunit M, archaeal; PFAM: Zinc finger, TFIIS-type; DNA-directed RNA polymerase, M/15kDa subunit; KEGG: mst:Msp_1533 RpoM1; SMART: Zinc finger, TFIIS-type; DNA-directed RNA polymerase, M/15kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
 
  
 0.565
csl4
RNA-binding domain, S1; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
       0.541
ADZ09014.1
TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; KEGG: mmg:MTBMA_c04870 biotin ligase; PFAM: Biotin/lipoate A/B protein ligase; Biotin protein ligase, C-terminal.
  
    0.502
ADZ09015.1
SMART: Biotin carboxylase, C-terminal; TIGRFAM: Acetyl-CoA carboxylase, biotin carboxylase; KEGG: mmg:MTBMA_c04880 pyruvate carboxylase, subunit A; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal.
       0.485
ADZ08332.1
KEGG: sfu:Sfum_0396 HAD superfamily hydrolase.
   
    0.473
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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