STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ09051.1PFAM: Protein of unknown function DUF106, transmembrane; KEGG: mmg:MTBMA_c05170 hypothetical protein. (193 aa)    
Predicted Functional Partners:
adkA
KEGG: msi:Msm_0737 adenylate kinase; HAMAP: Adenylate kinase; Belongs to the archaeal adenylate kinase family.
 
    0.954
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
 
    0.918
rpl15
50S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
    0.874
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
  
    0.773
ADZ09054.1
KEGG: mst:Msp_0880 50S ribosomal protein L14e.
 
     0.768
rpl30
KEGG: mmg:MTBMA_c05130 50S ribosomal protein L30P; TIGRFAM: Ribosomal protein L30, archaeal; PFAM: Ribosomal protein L30, ferredoxin-like fold domain.
 
    0.756
rpl34e
KEGG: mmg:MTBMA_c05180 50S ribosomal protein L34E; HAMAP: 50S ribosomal protein L34e; PFAM: Ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family.
 
     0.749
rpl19e
Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
 
    0.745
cmk
KEGG: msi:Msm_0734 cytidylate kinase; TIGRFAM: Cytidylate kinase, putative; HAMAP: Cytidylate kinase, putative.
 
     0.742
rpl18
Ribosomal protein L18P/L5E; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
     0.727
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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