STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cmkKEGG: msi:Msm_0734 cytidylate kinase; TIGRFAM: Cytidylate kinase, putative; HAMAP: Cytidylate kinase, putative. (176 aa)    
Predicted Functional Partners:
rpl34e
KEGG: mmg:MTBMA_c05180 50S ribosomal protein L34E; HAMAP: 50S ribosomal protein L34e; PFAM: Ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family.
  
    0.992
ADZ09054.1
KEGG: mst:Msp_0880 50S ribosomal protein L14e.
  
    0.987
truB
tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
      0.967
ADZ10737.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: mth:MTH1544 ribokinase; Belongs to the carbohydrate kinase PfkB family.
 
 
  0.929
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
 0.921
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
rpl14
50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
    0.883
rpl24
Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit.
  
    0.883
rpl4
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
  
    0.880
rpl22
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
  
    0.880
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.