Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
cmkKEGG: msi:Msm_0734 cytidylate kinase; TIGRFAM: Cytidylate kinase, putative; HAMAP: Cytidylate kinase, putative. (176 aa)    
Predicted Functional Partners:
rpl34e
KEGG: mmg:MTBMA_c05180 50S ribosomal protein L34E; HAMAP: 50S ribosomal protein L34e; PFAM: Ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family.
  
    0.991
ADZ09054.1
KEGG: mst:Msp_0880 50S ribosomal protein L14e.
  
    0.988
truB
tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
      0.973
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
 0.951
rpl14
50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
    0.944
rpl24
Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit.
  
    0.944
rpl22
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
  
    0.943
rps4e
HAMAP: Ribosomal protein S4e, archaea; PFAM: Ribosomal protein S4e, central; Ribosomal protein S4e, N-terminal; RNA-binding S4; KEGG: mmg:MTBMA_c05040 30S ribosomal protein S4e; SMART: RNA-binding S4; Belongs to the eukaryotic ribosomal protein eS4 family.
  
    0.943
rpl29
KEGG: msi:Msm_0755 50S ribosomal protein L29P; TIGRFAM: Ribosomal protein L29; PFAM: Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
 
    0.941
rpl5
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
  
    0.940
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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