| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ08346.1 | ADZ10127.1 | Metbo_0093 | Metbo_1907 | KEGG: mfv:Mfer_0053 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | KEGG: mmg:MTBMA_c11980 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | 0.494 |
| ADZ08346.1 | dapL | Metbo_0093 | Metbo_0824 | KEGG: mfv:Mfer_0053 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.423 |
| ADZ08667.1 | ADZ08830.1 | Metbo_0415 | Metbo_0579 | Lactaldehyde dehydrogenase; KEGG: msi:Msm_0467 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family. | HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily. | 0.936 |
| ADZ08667.1 | ADZ10127.1 | Metbo_0415 | Metbo_1907 | Lactaldehyde dehydrogenase; KEGG: msi:Msm_0467 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family. | KEGG: mmg:MTBMA_c11980 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | 0.593 |
| ADZ08667.1 | dapA | Metbo_0415 | Metbo_1906 | Lactaldehyde dehydrogenase; KEGG: msi:Msm_0467 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.577 |
| ADZ08667.1 | dapL | Metbo_0415 | Metbo_0824 | Lactaldehyde dehydrogenase; KEGG: msi:Msm_0467 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family. | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.448 |
| ADZ08830.1 | ADZ08667.1 | Metbo_0579 | Metbo_0415 | HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily. | Lactaldehyde dehydrogenase; KEGG: msi:Msm_0467 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family. | 0.936 |
| ADZ08830.1 | dapL | Metbo_0579 | Metbo_0824 | HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily. | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.504 |
| ADZ10127.1 | ADZ08346.1 | Metbo_1907 | Metbo_0093 | KEGG: mmg:MTBMA_c11980 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | KEGG: mfv:Mfer_0053 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 0.494 |
| ADZ10127.1 | ADZ08667.1 | Metbo_1907 | Metbo_0415 | KEGG: mmg:MTBMA_c11980 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | Lactaldehyde dehydrogenase; KEGG: msi:Msm_0467 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family. | 0.593 |
| ADZ10127.1 | dapA | Metbo_1907 | Metbo_1906 | KEGG: mmg:MTBMA_c11980 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.985 |
| ADZ10127.1 | dapB | Metbo_1907 | Metbo_1905 | KEGG: mmg:MTBMA_c11980 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.952 |
| ADZ10127.1 | dapF | Metbo_1907 | Metbo_0118 | KEGG: mmg:MTBMA_c11980 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. | 0.761 |
| ADZ10127.1 | dapL | Metbo_1907 | Metbo_0824 | KEGG: mmg:MTBMA_c11980 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.495 |
| ADZ10127.1 | lysA | Metbo_1907 | Metbo_0119 | KEGG: mmg:MTBMA_c11980 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.957 |
| dapA | ADZ08667.1 | Metbo_1906 | Metbo_0415 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Lactaldehyde dehydrogenase; KEGG: msi:Msm_0467 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family. | 0.577 |
| dapA | ADZ10127.1 | Metbo_1906 | Metbo_1907 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | KEGG: mmg:MTBMA_c11980 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | 0.985 |
| dapA | dapB | Metbo_1906 | Metbo_1905 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.998 |
| dapA | dapF | Metbo_1906 | Metbo_0118 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. | 0.903 |
| dapA | dapL | Metbo_1906 | Metbo_0824 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.511 |
