Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ09184.1TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; PAS fold; KEGG: mac:MA1270 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; PAC motif. (513 aa)    
Predicted Functional Partners:
ADZ10497.1
PFAM: MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal; MCP methyltransferase, CheR-type, all-alpha domain, N-terminal; KEGG: mbn:Mboo_0327 putative PAS/PAC sensor protein; SMART: MCP methyltransferase, CheR-type.
   
 0.794
ADZ09478.1
KEGG: mac:MA1268 response regulator receiver; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.
   
 0.789
ADZ09346.1
KEGG: mmg:MTBMA_c08410 sensory transduction regulatory protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.
 
   
 0.754
ADZ09479.1
Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: PAS fold; Signal transduction response regulator, receiver domain; KEGG: bph:Bphy_1145 multi-sensor signal transduction histidine kinase; SMART: Signal transduction response regulator, receiver domain; PAS; PAC motif.
   
 0.739
ADZ09861.1
Hypothetical protein; KEGG: mac:MA1269 response regulator receiver.
 
   
 0.737
ADZ09291.1
Response regulator receiver protein; KEGG: nhl:Nhal_1443 PAS sensor protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.
   
 0.675
ADZ09183.1
Hypothetical protein.
       0.558
ADZ09568.1
MCP methyltransferase/methylesterase, CheR/CheB; PFAM: MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal; Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; MCP methyltransferase, CheR-type, all-alpha domain, N-terminal; KEGG: mbn:Mboo_0327 putative PAS/PAC sensor protein; SMART: MCP methyltransferase, CheR-type.
   
 0.532
ADZ10093.1
Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: PAS fold-3; PAS fold-4; PAS fold; KEGG: sfu:Sfum_2638 signal transduction histidine kinase; SMART: PAS; PAC motif.
 
   
0.457
ADZ09388.1
Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: Signal transduction response regulator, receiver domain; PAS fold-4; KEGG: mth:MTH440 sensory transduction regulatory protein; SMART: Signal transduction response regulator, receiver domain; PAS; PAC motif.
   
 0.414
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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