Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
tgtA7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (678 aa)    
Predicted Functional Partners:
nac
Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.985
ADZ09209.1
KEGG: mmg:MTBMA_c06330 hypothetical protein.
       0.960
ADZ09210.1
KEGG: mmg:MTBMA_c06320 hypothetical protein.
       0.960
ADZ08960.1
PFAM: Phosphate transporter; KEGG: mth:MTH1885 sodium-dependent phosphate transporter.
  
    0.943
ADZ09104.1
PFAM: Glycosyl transferase, family 2; KEGG: has:Halsa_0644 undecaprenyl-phosphate galactose phosphotransferase.
   
   0.924
ADZ09214.1
PFAM: Domain of unknown function DUF752; KEGG: mmg:MTBMA_c06280 hypothetical protein.
     
 0.923
ADZ09211.1
Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: mmg:MTBMA_c06310 phosphohydrolase.
  
    0.912
ADZ08843.1
Manually curated; PFAM: ABC transporter-like; RNase L inhibitor RLI, possible metal-binding domain; 4Fe-4S binding domain; KEGG: mth:MTH1695 putative ATPase RIL; SMART: ATPase, AAA+ type, core.
  
    0.905
pth
Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
       0.892
ADZ10258.1
PUA domain containing protein; KEGG: mst:Msp_1063 RNA-binding protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase.
 
  
0.870
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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