Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ09224.1KEGG: mru:mru_1212 CoB--CoM heterodisulfide reductase subunitB HdrB2; PFAM: Cysteine-rich domain. (239 aa)    
Predicted Functional Partners:
ADZ09225.1
Lactate utilization protein B/C; PFAM: Domain of unknown function DUF162; KEGG: mmg:MTBMA_c05900 conserved iron-sulfur cluster binding protein.
 
 0.997
ADZ09223.1
PFAM: Glycosyl transferase, family 2; KEGG: mev:Metev_2282 glycosyl transferase family 2.
     
 0.534
ADZ10490.1
PFAM: Protein of unknown function DUF116; KEGG: mth:MTH559 hypothetical protein.
       0.516
gap
KEGG: mth:MTH1009 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type II; HAMAP: Glyceraldehyde-3-phosphate dehydrogenase; SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain.
  
  
 0.494
gap-2
KEGG: mmg:MTBMA_c13910 glyceraldehyde 3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type II; HAMAP: Glyceraldehyde-3-phosphate dehydrogenase; SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain.
  
  
 0.494
ADZ09226.1
Hypothetical protein.
       0.442
ADZ08667.1
Lactaldehyde dehydrogenase; KEGG: msi:Msm_0467 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family.
 
  
 0.419
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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