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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (203 aa)    
Predicted Functional Partners:
ADZ08399.1
TIGRFAM: Molybdenum cofactor synthesis; PFAM: MoeA, N-terminal and linker domain; Molybdopterin binding; MoeA, C-terminal, domain IV; KEGG: mmg:MTBMA_c17560 molybdenum cofactor biosynthesis protein; SMART: Molybdopterin binding.
 
 0.980
fdhD
Protein fdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
 
 0.913
ADZ10729.1
KEGG: tpd:Teth39_0854 putative molybdopterin-guanine dinucleotide biosynthesis protein MobB/FeS domain-containing protein protein; TIGRFAM: Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB), conserved domain; PFAM: Putative Fe-S cluster.
 
 
 0.891
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
  
 0.818
ADZ10716.1
Putative transcriptional regulator, ModE family; PFAM: Transport-associated OB, type 1; HTH transcriptional regulator, LysR; KEGG: msi:Msm_1207 molybdate transport system regulatory protein.
 
   
 0.806
ADZ10728.1
TIGRFAM: Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S binding domain; Molydopterin dinucleotide-binding domain; KEGG: mth:MTH1552 formate dehydrogenase, alpha subunit-like protein; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding.
 
   
 0.753
ADZ10583.1
TIGRFAM: Molybdenum cofactor synthesis; PFAM: MoeA, N-terminal and linker domain; Molybdopterin binding; MoeA, C-terminal, domain IV; KEGG: mfv:Mfer_0296 molybdenum cofactor synthesis domain protein; SMART: Molybdopterin binding.
 
 
 0.738
ADZ08931.1
TIGRFAM: Molybdenum cofactor synthesis; PFAM: Molybdopterin binding; KEGG: mth:MTH1861 molybdenum cofactor biosynthesis MoaB; SMART: Molybdopterin binding.
 
  
 0.635
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.619
ADZ09238.1
PFAM: Molybdopterin biosynthesis MoaE; KEGG: mru:mru_1268 molybdenum cofactor biosynthesis protein MoaE.
 
  
 0.619
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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