STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (186 aa)    
Predicted Functional Partners:
ADZ08430.1
UbiD family decarboxylase; KEGG: mst:Msp_1479 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: Carboxylyase-related; PFAM: Carboxylyase-related.
 
  
 0.938
cbiT
cobalt-precorrin-6Y C(15)-methyltransferase (decarboxylating); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
       0.927
ADZ09237.1
KEGG: mth:MTH148 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain.
  
    0.859
ADZ09238.1
PFAM: Molybdopterin biosynthesis MoaE; KEGG: mru:mru_1268 molybdenum cofactor biosynthesis protein MoaE.
     
 0.810
ADZ08354.1
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
       0.778
ADZ09234.1
KEGG: mth:MTH145 hypothetical protein.
       0.700
ADZ09239.1
PFAM: Cytidylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; KEGG: mmg:MTBMA_c06000 nicotinamide-nucleotide adenylyltransferase.
       0.670
ADZ09233.1
PFAM: Pseudomurein-binding repeat; KEGG: mmg:MTBMA_c05940 hypothetical protein.
       0.441
ADZ09422.1
KEGG: mvn:Mevan_0177 serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase.
       0.412
cofH
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine.
 
   
 0.404
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (28%) [HD]
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