STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ09243.1PFAM: UspA; KEGG: mth:MTH153 hypothetical protein. (133 aa)    
Predicted Functional Partners:
ADZ09242.1
ABC transporter related protein; KEGG: mmg:MTBMA_c06010 methyl-coenzyme M reductase component A2-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.
  
    0.839
ADZ08818.1
TIGRFAM: Acetate-CoA ligase; KEGG: mmg:MTBMA_c01900 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase/ligase.
     
 0.576
cdhA
Acetyl-CoA decarbonylase/synthase complex subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
     
 0.558
ADZ10423.1
Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c11350 CBS domain containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
  
  
 0.537
ADZ09244.1
Hypothetical protein.
       0.523
ADZ08721.1
KEGG: mfv:Mfer_0521 methylated-DNA/protein-cysteinemethyltransferase; TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding.
  
    0.440
ogt
methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
    0.440
ADZ08383.1
PFAM: Isochorismatase-like; KEGG: mpl:Mpal_1179 isochorismatase hydrolase.
 
  
 0.436
ADZ08550.1
CBS domain containing membrane protein; KEGG: mth:MTH1222 inosine-5'-monophosphate dehydrogenase related protein I; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
 
  
 0.416
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.