Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ09250.1Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (228 aa)    
Predicted Functional Partners:
ADZ08748.1
PFAM: Thioredoxin domain; KEGG: mth:MTH1745 protein disulphide isomerase.
  
 0.951
ADZ10132.1
Redox-active disulfide protein 1; KEGG: mmg:MTBMA_c12030 thioredoxin; TIGRFAM: Thioredoxins/glutaredoxin; PFAM: Glutaredoxin.
  
 0.951
ADZ10659.1
KEGG: mmg:MTBMA_c10960 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.933
ADZ09251.1
Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.927
hcp
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
 
 0.905
hcp-2
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
 
 0.905
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 
 0.896
ADZ09248.1
Ferroxidase; KEGG: mmg:MTBMA_c06090 ferritin; PFAM: Ferritin/Dps protein.
  
  
 0.872
rpl4
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
   
 
 0.786
ADZ08502.1
Phosphodiesterase, MJ0936 family; KEGG: mmg:MTBMA_c16490 phosphodiesterase; TIGRFAM: Phosphodiesterase MJ0936; PFAM: Metallo-dependent phosphatase.
 
 
 0.782
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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