Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
ADZ09347.1Histidine kinase; KEGG: mth:MTH444 sensory transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain. (291 aa)    
Predicted Functional Partners:
ADZ09346.1
KEGG: mmg:MTBMA_c08410 sensory transduction regulatory protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.
 
   
 0.916
ADZ10497.1
PFAM: MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal; MCP methyltransferase, CheR-type, all-alpha domain, N-terminal; KEGG: mbn:Mboo_0327 putative PAS/PAC sensor protein; SMART: MCP methyltransferase, CheR-type.
   
 0.877
ADZ09478.1
KEGG: mac:MA1268 response regulator receiver; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.
   
 0.807
ADZ09568.1
MCP methyltransferase/methylesterase, CheR/CheB; PFAM: MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal; Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; MCP methyltransferase, CheR-type, all-alpha domain, N-terminal; KEGG: mbn:Mboo_0327 putative PAS/PAC sensor protein; SMART: MCP methyltransferase, CheR-type.
   
 0.771
ADZ09479.1
Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: PAS fold; Signal transduction response regulator, receiver domain; KEGG: bph:Bphy_1145 multi-sensor signal transduction histidine kinase; SMART: Signal transduction response regulator, receiver domain; PAS; PAC motif.
   
 0.767
ADZ09345.1
TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold; ATPase-like, ATP-binding domain; KEGG: mth:MTH902 sensory transduction histidine kinase; SMART: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain.
   
 0.737
ADZ09981.1
PFAM: Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal; UspA; KEGG: mbn:Mboo_0896 osmosensitive K+ channel His kinase sensor.
 
      0.720
ADZ10280.1
Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: Signal transduction response regulator, receiver domain; PAS fold-4; KEGG: gur:Gura_1549 multi-sensor signal transduction histidine kinase; SMART: Signal transduction response regulator, receiver domain; PAS; PAC motif.
   
 0.643
ADZ09344.1
KEGG: mmg:MTBMA_c08430 sensory transduction regulatory protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.
       0.633
ADZ09388.1
Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: Signal transduction response regulator, receiver domain; PAS fold-4; KEGG: mth:MTH440 sensory transduction regulatory protein; SMART: Signal transduction response regulator, receiver domain; PAS; PAC motif.
    
 0.578
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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