Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADZ09359.1PFAM: Restriction endonuclease, type I, S subunit, EcoBI; KEGG: mmw:Mmwyl1_3199 restriction modification system DNA specificity subunit. (403 aa)    
Predicted Functional Partners:
ADZ09358.1
PFAM: DNA methylase, adenine-specific; KEGG: mmq:MmarC5_1169 N-6 DNA methylase.
 
 
 0.999
ADZ09361.1
Type I site-specific deoxyribonuclease; SMART: DEAD-like helicase, N-terminal; manually curated; KEGG: mmq:MmarC5_1171 type III restriction enzyme, res subunit; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Helicase, C-terminal.
 
 
 0.992
ADZ09357.1
KEGG: mta:Moth_1666 hypothetical protein.
       0.773
ADZ09360.1
PFAM: SEC-C motif; KEGG: hna:Hneap_1661 hypothetical protein.
       0.709
ADZ10368.1
Type II site-specific deoxyribonuclease; KEGG: abi:Aboo_1333 protein of unknown function DUF450; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; DNA methylase, adenine-specific.
 
  
 0.663
ADZ09355.1
KEGG: cte:CT1466 TIR domain-containing protein; PFAM: Toll-Interleukin receptor; SMART: Toll-Interleukin receptor.
 
     0.638
ADZ09783.1
KEGG: mbu:Mbur_2163 hypothetical protein.
 
  
 0.637
ADZ09781.1
KEGG: hso:HS_1260 hypothetical protein.
 
  
 0.580
ADZ08916.1
PFAM: Protein of unknown function DUF45; KEGG: mmh:Mmah_0029 protein of unknown function DUF45.
 
    0.572
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.538
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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