Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADZ09518.1NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c07980 energy-converting hydrogenase A, subunit O; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit. (381 aa)    
Predicted Functional Partners:
ADZ09519.1
PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: mmg:MTBMA_c07970 energy-converting hydrogenase A, subunit N.
 
 
 0.998
ADZ08524.1
PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: mmg:MTBMA_c16270 energy-converting hydrogenase B, subunit M.
 
 
 0.996
ADZ08517.1
NADH dehydrogenase (quinone); KEGG: mth:MTH1246 hydrogenase subunit F; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase.
 
 
 0.988
ADZ09523.1
PFAM: NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H; KEGG: mth:MTH393 NADH dehydrogenase (ubiquinone), subunit 1 related protein.
 
 
 0.988
ADZ08511.1
PFAM: cation antiporter; KEGG: mmg:MTBMA_c16390 energy-converting hydrogenase B, subunit A.
 
 
 0.960
ADZ08526.1
KEGG: mth:MTH1237 NADH dehydrogenase (ubiquinone), subunit 1 related protein.
 
 
 0.942
ADZ09521.1
PFAM: Protein of unknown function DUF2104, membrane; KEGG: mru:mru_1401 energy-converting hydrogenase A subunit L EhaL.
     
 0.901
ADZ09517.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; KEGG: mmg:MTBMA_c07990 energy-converting hydrogenase A, subunit P.
  
    0.894
ADZ09525.1
PFAM: [NiFe]-hydrogenase-3-type complex Eha, membrane protein EhaH, predicted; KEGG: mth:MTH391 NADH dehydrogenase I, subunit N related protein.
     
 0.894
ADZ09520.1
PFAM: [NiFe]-hydrogenase-3-type complex Eha, EhaM; KEGG: mth:MTH396 hypothetical protein.
  
    0.889
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (18%) [HD]