STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ09608.1Protein of unknown function UPF0058; PFAM: Uncharacterised protein family UPF0058; KEGG: mmg:MTBMA_c06730 hypothetical protein. (109 aa)    
Predicted Functional Partners:
ADZ10340.1
Regulatory protein Crp; SMART: HTH transcriptional regulator, Crp; KEGG: mst:Msp_1188 transcriptional regulator.
 
     0.692
ADZ08794.1
Queuosine synthesis-like protein; PFAM: Queuosine synthesis; KEGG: mfv:Mfer_0169 queuosine synthesis.
  
     0.648
ADZ08348.1
UPF0285 protein; KEGG: mmg:MTBMA_c00280 putative carbohydrate kinase of the FGGY family; TIGRFAM: Uncharacterised protein family UPF0285, methanogenesis; HAMAP: Uncharacterised protein family UPF0285, methanogenesis; Belongs to the UPF0285 family.
  
     0.572
rnp3
Ribonuclease P protein component 3; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
     0.572
gch3
GTP cyclohydrolase III; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.
  
     0.567
ADZ09186.1
Phosphoesterase RecJ domain protein; KEGG: mmg:MTBMA_c11580 archaea-specific RecJ-like exonuclease; PFAM: Phosphoesterase, RecJ-like; Nucleic acid binding, OB-fold, tRNA/helicase-type; Ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1.
  
   
 0.565
ADZ08584.1
KEGG: mth:MTH1192 hypothetical protein.
  
     0.564
ADZ09418.1
PFAM: Amino acid-binding ACT; KEGG: msi:Msm_0155 allosteric regulator of homoserine dehydrogenase.
  
     0.544
ADZ08989.1
PFAM: Uncharacterised conserved protein UCP004977; KEGG: mmg:MTBMA_c04760 hypothetical protein.
  
   
 0.528
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
       0.512
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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