STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ09617.1Propanoyl-CoA C-acyltransferase; KEGG: mmg:MTBMA_c11890 acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal. (383 aa)    
Predicted Functional Partners:
ADZ08434.1
PFAM: Domain of unknown function DUF35, OB-fold, C-terminal; KEGG: mmg:MTBMA_c17840 nucleic acid-binding protein.
 
 
 0.999
ADZ09618.1
UPF0219 protein; TIGRFAM: Putative condensing enzyme FabH-related; HAMAP: Putative condensing enzyme FabH-related; KEGG: mmg:MTBMA_c11880 3-hydroxy-3-methylglutaryl-CoA-synthase; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal; Hydroxymethylglutaryl-coenzyme A synthase, N-terminal; Belongs to the thiolase-like superfamily. UPF0219 family.
 
 0.999
ADZ09877.1
CoA-binding domain protein; KEGG: mbu:Mbur_1347 acyl-CoA synthetase; PFAM: CoA-binding; SMART: CoA-binding.
 
 
 0.967
ADZ09939.1
acetate/CoA ligase; PFAM: AMP-dependent synthetase/ligase; manually curated; KEGG: mth:MTH217 acetyl-CoA synthetase; TIGRFAM: Acetate-CoA ligase.
  
 
 0.960
ADZ10668.1
Butyrate--CoA ligase; KEGG: mba:Mbar_A2172 AMP-binding protein; PFAM: AMP-dependent synthetase/ligase.
  
 
 0.960
ADZ08818.1
TIGRFAM: Acetate-CoA ligase; KEGG: mmg:MTBMA_c01900 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase/ligase.
  
 
 0.959
ADZ10118.1
TIGRFAM: Acetate-CoA ligase; KEGG: mfv:Mfer_0074 acetyl-coenzyme a synthetase; PFAM: AMP-dependent synthetase/ligase.
  
 
 0.959
ADZ08319.1
SMART: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; TIGRFAM: Isopropylmalate/citramalate/homocitrate synthase; KEGG: mth:MTH1481 2-isopropylmalate synthase; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.948
ADZ10290.1
TIGRFAM: Isopropylmalate/citramalate/homocitrate synthase; KEGG: mmg:MTBMA_c02150 2-isopropylmalate synthase; PFAM: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.948
cdhE
CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
     
 0.928
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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