STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ09618.1UPF0219 protein; TIGRFAM: Putative condensing enzyme FabH-related; HAMAP: Putative condensing enzyme FabH-related; KEGG: mmg:MTBMA_c11880 3-hydroxy-3-methylglutaryl-CoA-synthase; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal; Hydroxymethylglutaryl-coenzyme A synthase, N-terminal; Belongs to the thiolase-like superfamily. UPF0219 family. (349 aa)    
Predicted Functional Partners:
ADZ08878.1
TIGRFAM: Hydroxymethylglutaryl-CoA reductase, eukaryotic/arcaheal type; KEGG: mfv:Mfer_0012 3-hydroxy-3-methylglutaryl-coenzyme a reductase; PFAM: Hydroxymethylglutaryl-CoA reductase, class I/II; Belongs to the HMG-CoA reductase family.
 
 0.999
ADZ09617.1
Propanoyl-CoA C-acyltransferase; KEGG: mmg:MTBMA_c11890 acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal.
 
 0.999
ADZ08434.1
PFAM: Domain of unknown function DUF35, OB-fold, C-terminal; KEGG: mmg:MTBMA_c17840 nucleic acid-binding protein.
 
 
 0.998
ADZ08739.1
KEGG: mth:MTH1738 pyruvate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
    
 0.909
ADZ09694.1
TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: ppd:Ppro_0548 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
    
 0.908
ADZ10620.1
KEGG: mth:MTH1034 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
    
 0.908
ADZ10663.1
TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: mmg:MTBMA_c09240 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
    
 0.908
ADZ08740.1
KEGG: mmg:MTBMA_c03140 pyruvate synthase, subunit A; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal.
    
  0.902
ADZ08741.1
KEGG: mmg:MTBMA_c03150 pyruvate synthase, subunit D; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; PFAM: 4Fe-4S binding domain.
    
  0.902
ADZ08742.1
TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; KEGG: mth:MTH1740 pyruvate ferredoxin oxidoreductase subunit gamma/delta; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
    
  0.902
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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