STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ogtmethylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (190 aa)    
Predicted Functional Partners:
ADZ08382.1
KEGG: glo:Glov_0058 DNA-3-methyladenine glycosylase I; PFAM: Methyladenine glycosylase.
    
 0.792
ADZ09944.1
PFAM: Cation/H+ exchanger; KEGG: gfo:GFO_0816 sodium/hydrogen exchanger family protein.
     
 0.514
ADZ08291.1
PFAM: Nucleotidyl transferase; KEGG: mmg:MTBMA_c01060 nucleotidyl transferase.
     
 0.469
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
 
  
 0.441
ADZ09243.1
PFAM: UspA; KEGG: mth:MTH153 hypothetical protein.
  
    0.440
ADZ09280.1
PFAM: UspA; KEGG: mth:MTH993 hypothetical protein.
  
    0.440
ADZ09332.1
PFAM: UspA; KEGG: mmg:MTBMA_c14530 universal stress protein.
  
    0.440
ADZ09981.1
PFAM: Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal; UspA; KEGG: mbn:Mboo_0896 osmosensitive K+ channel His kinase sensor.
  
    0.440
ADZ09987.1
PFAM: UspA; KEGG: mth:MTH993 hypothetical protein.
  
    0.440
ADZ10445.1
PFAM: UspA; KEGG: mmg:MTBMA_c13760 universal stress protein.
  
    0.440
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.