| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ09420.1 | ADZ09625.1 | Metbo_1176 | Metbo_1385 | KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | PFAM: Xanthine/uracil/vitamin C permease; KEGG: mpd:MCP_1361 xanthine/uracil/vitamin C permease family protein. | 0.490 |
| ADZ09420.1 | hpt | Metbo_1176 | Metbo_0197 | KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.717 |
| ADZ09420.1 | purC | Metbo_1176 | Metbo_2114 | KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: SAICAR synthetase; HAMAP: SAICAR synthetase; KEGG: mth:MTH170 phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.977 |
| ADZ09420.1 | purD | Metbo_1176 | Metbo_0091 | KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: mfv:Mfer_0051 phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.960 |
| ADZ09420.1 | purE | Metbo_1176 | Metbo_0177 | KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.933 |
| ADZ09420.1 | purL | Metbo_1176 | Metbo_0153 | KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.993 |
| ADZ09420.1 | purM | Metbo_1176 | Metbo_0321 | KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: msi:Msm_1039 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase-related protein; AIR synthase-related protein, C-terminal. | 0.941 |
| ADZ09420.1 | purQ | Metbo_1176 | Metbo_2116 | KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.945 |
| ADZ09420.1 | purS | Metbo_1176 | Metbo_2115 | KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.932 |
| ADZ09625.1 | ADZ09420.1 | Metbo_1385 | Metbo_1176 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: mpd:MCP_1361 xanthine/uracil/vitamin C permease family protein. | KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | 0.490 |
| ADZ09625.1 | hpt | Metbo_1385 | Metbo_0197 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: mpd:MCP_1361 xanthine/uracil/vitamin C permease family protein. | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.613 |
| ADZ09625.1 | purC | Metbo_1385 | Metbo_2114 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: mpd:MCP_1361 xanthine/uracil/vitamin C permease family protein. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: SAICAR synthetase; HAMAP: SAICAR synthetase; KEGG: mth:MTH170 phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.637 |
| ADZ09625.1 | purD | Metbo_1385 | Metbo_0091 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: mpd:MCP_1361 xanthine/uracil/vitamin C permease family protein. | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: mfv:Mfer_0051 phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.661 |
| ADZ09625.1 | purE | Metbo_1385 | Metbo_0177 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: mpd:MCP_1361 xanthine/uracil/vitamin C permease family protein. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.648 |
| ADZ09625.1 | purF | Metbo_1385 | Metbo_2098 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: mpd:MCP_1361 xanthine/uracil/vitamin C permease family protein. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.444 |
| ADZ09625.1 | purL | Metbo_1385 | Metbo_0153 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: mpd:MCP_1361 xanthine/uracil/vitamin C permease family protein. | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.637 |
| ADZ09625.1 | purM | Metbo_1385 | Metbo_0321 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: mpd:MCP_1361 xanthine/uracil/vitamin C permease family protein. | TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: msi:Msm_1039 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase-related protein; AIR synthase-related protein, C-terminal. | 0.629 |
| ADZ09625.1 | purQ | Metbo_1385 | Metbo_2116 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: mpd:MCP_1361 xanthine/uracil/vitamin C permease family protein. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.617 |
| ADZ09625.1 | purS | Metbo_1385 | Metbo_2115 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: mpd:MCP_1361 xanthine/uracil/vitamin C permease family protein. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.508 |
| hpt | ADZ09420.1 | Metbo_0197 | Metbo_1176 | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | 0.717 |
