STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ09944.1PFAM: Cation/H+ exchanger; KEGG: gfo:GFO_0816 sodium/hydrogen exchanger family protein. (397 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.939
ADZ09712.1
Heat shock protein DnaJ domain protein; KEGG: pfh:PFHG_00645 hypothetical protein similar to chaperone protein J; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal.
     
 0.937
ADZ08807.1
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
  
    0.898
ADZ08931.1
TIGRFAM: Molybdenum cofactor synthesis; PFAM: Molybdopterin binding; KEGG: mth:MTH1861 molybdenum cofactor biosynthesis MoaB; SMART: Molybdopterin binding.
     
 0.889
ADZ10303.1
TIGRFAM: UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal type; KEGG: mmg:MTBMA_c10160 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase.
     
 0.829
ADZ08895.1
PFAM: Mechanosensitive ion channel MscS; KEGG: mmg:MTBMA_c04000 mechanosensitive ion channel.
 
   
 0.812
ADZ08355.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
     
 0.807
ADZ08496.1
KEGG: mmg:MTBMA_c16510 potassium uptake protein TrkH; TIGRFAM: Potassium uptake protein TrkH; PFAM: Cation transporter.
     
 0.801
ADZ09281.1
PFAM: Cation transporter; KEGG: mst:Msp_0830 trk-type potassium transport system, membrane protein.
     
 0.801
ADZ08495.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: mth:MTH1265 trk system potassium uptake protein TrkA.
    
 0.794
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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