Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10072.1PFAM: SirA-like; KEGG: mbu:Mbur_0089 SirA-like protein. (104 aa)    
Predicted Functional Partners:
ADZ10071.1
KEGG: mmh:Mmah_0897 uncharacterized NAD(FAD)-dependent dehydrogenase.
 
  
 0.970
ADZ10070.1
KEGG: mma:MM_1955 cysteine desulfurase NifS; PFAM: Aminotransferase, class V/Cysteine desulfurase.
 
 
 
 0.938
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
 
 
 0.853
ADZ09422.1
KEGG: mvn:Mevan_0177 serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase.
     
 0.672
ADZ09473.1
KEGG: msi:Msm_0263 nitrogen fixation protein, NifU; TIGRFAM: NIF system FeS cluster assembly, NifU-like; PFAM: NIF system FeS cluster assembly, NifU, N-terminal.
     
 0.599
ADZ08706.1
Beta-lactamase domain protein; KEGG: mmg:MTBMA_c14810 hydrolase; PFAM: Beta-lactamase-like; Rhodanese-like; SMART: Beta-lactamase-like; Rhodanese-like.
  
  
 0.570
ADZ09297.1
KEGG: mpl:Mpal_2117 rhodanese domain protein; PFAM: Rhodanese-like; SMART: Rhodanese-like.
  
  
 0.570
ADZ09680.1
DsrE family protein; PFAM: Sulphur relay, DsrE/F-like protein; SirA-like; KEGG: mmg:MTBMA_c00060 peroxiredoxin-related protein.
 
   
 0.543
ADZ10073.1
Cyclase family protein; PFAM: Putative cyclase; KEGG: mmg:MTBMA_c03680 metal-dependent hydrolase.
       0.540
ADZ09423.1
TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; KEGG: mru:mru_1574 cysteine synthase CysKM1; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit.
  
  
 0.500
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.