STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10095.1Phosphoesterase; KEGG: mmg:MTBMA_c03740 phosphoesterase; TIGRFAM: Conserved hypothetical protein CHP00024; PFAM: Metallo-dependent phosphatase. (245 aa)    
Predicted Functional Partners:
ADZ10094.1
DEAD/H associated domain protein; KEGG: mth:MTH1802 ATP-dependent helicase; PFAM: DEAD/H associated; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; ATPase, AAA+ type, core; Helicase, C-terminal.
 
    0.962
lig
DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
   
 0.497
ADZ08444.1
PFAM: Protein of unknown function DUF655; KEGG: mth:MTH1325 hypothetical protein.
  
     0.484
ADZ10598.1
PFAM: DNA ligase, ATP-dependent, central; DNA ligase, ATP-dependent, C-terminal; KEGG: afu:AF1725 DNA ligase, putative.
 
   
 0.484
dnaG
UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
     0.444
ADZ08468.1
TIGRFAM: Conserved hypothetical protein CHP00061; KEGG: mmg:MTBMA_c16880 hypothetical protein.
  
     0.435
ADZ10093.1
Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: PAS fold-3; PAS fold-4; PAS fold; KEGG: sfu:Sfum_2638 signal transduction histidine kinase; SMART: PAS; PAC motif.
       0.417
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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