STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10129.1TIGRFAM: Chorismate mutase, archaeal; PFAM: Chorismate mutase, type II; KEGG: mfv:Mfer_0679 chorismate mutase, type II; SMART: Chorismate mutase. (97 aa)    
Predicted Functional Partners:
rps17e
KEGG: msi:Msm_0833 30S ribosomal protein S17e; HAMAP: Ribosomal protein S17e; PFAM: Ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
  
    0.984
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.981
ADZ10282.1
KEGG: mfv:Mfer_0622 prephenate dehydrogenase.
  
 
 0.963
ADZ08552.1
KEGG: mmg:MTBMA_c16050 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT.
  
 
 0.949
ADZ10266.1
TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain; KEGG: mfv:Mfer_0097 anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I, C-terminal.
  
 
 0.948
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
  
 
 0.948
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
  
 0.938
aroK
PFAM: GHMP kinase; GHMP kinase, C-terminal; TIGRFAM: Shikimate kinase, archaea; HAMAP: Shikimate kinase; KEGG: mfv:Mfer_0680 shikimate kinase.
       0.911
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
  
 0.879
ADZ10288.1
PFAM: Protein of unknown function DUF98; KEGG: mth:MTH1632 hypothetical protein.
    
 0.853
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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