Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10220.1PFAM: UbiA prenyltransferase; KEGG: mem:Memar_2408 UbiA prenyltransferase. (307 aa)    
Predicted Functional Partners:
ADZ10221.1
PFAM: UbiA prenyltransferase; KEGG: mem:Memar_2408 UbiA prenyltransferase.
 
  
 
0.965
ADZ08878.1
TIGRFAM: Hydroxymethylglutaryl-CoA reductase, eukaryotic/arcaheal type; KEGG: mfv:Mfer_0012 3-hydroxy-3-methylglutaryl-coenzyme a reductase; PFAM: Hydroxymethylglutaryl-CoA reductase, class I/II; Belongs to the HMG-CoA reductase family.
   
 
 0.738
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
 0.532
ADZ09682.1
GAF domain protein; KEGG: mpi:Mpet_0436 putative GAF sensor protein; PFAM: GAF; SMART: GAF.
  
     0.478
ADZ09629.1
KEGG: mmg:MTBMA_c08760 hypothetical protein.
  
     0.473
ADZ08419.1
Replication factor-A domain protein; PFAM: Replication factor A, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmg:MTBMA_c17710 replication factor A.
  
 
   0.423
ADZ10536.1
PFAM: Nitrogen regulatory protein PII; KEGG: mmg:MTBMA_c11600 small GTPase.
  
     0.423
ADZ08402.1
PFAM: ABC-2 type transporter; KEGG: mmg:MTBMA_c17580 ABC transporter, permease component.
 
     0.419
ADZ10683.1
KEGG: mpd:MCP_0447 hypothetical protein.
 
     0.417
ADZ10689.1
KEGG: mla:Mlab_0256 periplasmic binding protein.
 
     0.417
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.